Universidade do Minho
Escola de Engenharia
Dept. Electrónica Industrial
MOMBaker
Bioreactor-on-a-chip (sponsored by UM/Center Algoritmi)
Abstract
This project consists on a miniaturized bioreactor (bioreactor-on-a-chip) applied to baker's yeast fermentation. The bioreactor-on-a-chip is fabricated using a silicon and glass wafers applying micromachining technology (wet-etching techniques) in order to create microchannels, mixerchannels and microvalves. The miniaturization and integration allows smaller volumes to be used, which can be often rather challenging from the analytical point of view. Also, optical detection by absorption, electrochemical detection using microelectrodes and membranes are used. Moreover, electroanalytical techniques used in bioelectrochemistry (e.g. microdialysis, capillary electrophoresis and HPLC) are employed.
Publications
Conference Publications:
1. F. O. Soares, J. H. Correia, Bioareactor-on-a chip: application to Baker's yeast fermentation, Proc. 1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine & Biology, full paper in Acrobat PDF, Lyon, França, 12-14 Outubro, pp. 45-48, 2000.
2. F. O. Soares, Pedro Gomes, J. H. Correia, A bioareactor based on optical measurements for Baker's yeast fermentation, Proc. Eurosensors XVI, full paper in Acrobat PDF, Prague, Rep. Checa, 15-18 Setembro, pp.1121-1122 , 2002.
Researchers
Pedro Gomes (DEI)
Graça Maria Henriques Minas (DEI)
José Higino Gomes Correia (DEI)
Filomena Soares (DEI)
Áreas de Investigação e Orientações